Sandrine's father is dead, and her mother has vanished into her immense grief and sorrow. Alone and suffering from an incurable disease, the eleven-year-old girl finds companionship in her doctor, Tiresias, who morphologically changes sex in unpredictable ways (and seemingly without anyone noticing). A transformational tale about the mysteries of identity and the power dynamics that surround it, The Neptune Roompieces together life's terrible but tender metamorphosis, opening a door onto a universe of beauty, mourning, and renewal.